For wheelguns, I like the Hogue monogrips best. The open backstrap works for my short fingers, and the gentle continuation of the curve at the top back of the grip where the frame widens out is the most comfortable for absorbing recoil.
Pachmayers had a too-square edge up there and were noticeably more uncomfortable when shooting way-stout 146- and 158-gr loads in .357 mag.
BTW, I first got into the Hogues when they were hard plastic, and still prefer that type. An off-brand rubber grip with closed backstrap was less comfortable, because the rear surface was too narrow. A broad, smooth surface works best for me, even if it's steel or hard plastic.
edit-
This is all despite the fingergrooves. They don't really fit me. A single groove like the AR15A2's grip would be ideal. Now that I think about it, maybe it's time to grind off the last two ridges on mine...
[This message has been edited by Cheapo (edited January 15, 2000).]