Yes.
It's not a question of if, it's a matter of when.
Mine went a couple thousand rounds of normal .38's then it started to lose bits on the face of the cylinder. Once it starts, it goes downhill fast.
I view it as the price to pay for a nickel finish, and accept it as normal wear and tear.
The enjoyment I've gotten out of that gun over the years, as well as it "being there" a few times when I packed it along as a camp gun make up for it in spades.
It's honest wear as opposed to damage done by neglect or using the wrong cleaning agents.
I also bought a 4" nickel 19 that I don't plan on shooting anywhere near as much as the old 6". If it does show signs, then *shrug* *oh well*. I'll look back at it also as being a source of enjoyment.