From coltsmfg.com FAQ's.
"Is there a Colt service center in my area? No. Any service repairs under the Lifetime Service Agreement (for firearms produced after 1996) must be made at the factory for quality control purposes. If any repairs are attempted outside of the factory, the Lifetime Service Agreement will be VOIDED."
"Please dial 1-800-962-2658 and follow the menu for the department you wish to reach."
Mind you, like Jim says, sort of, fixed how? Pythons were hand finished in the factory. That's why they're $1,000 .357 revolvers. You don't want just anybody working on it. Cylinder and Slide isn't just anybody though.