On this rifle I have a scope with a BDC reticle. I keep notes on my loads, including POI in relation to the BDC along with BC of the bullet and drop.
It really is not that difficult to memorize which line corresponds to which load at what distances; then again I always test out my loads at the range with a chrono and actual targets at varying ranges. And if I am not sure, I always have the numbers stuck to the bottom of the mag; I just write down the drop on paper and affix it to the bottom and keep a copy in my pocket in case it falls off during use.
I generally don't adjust my scope, I keep it set to my "favorite" hunting load, and then adjust everything else to that standard.