I carry mine with the safety OFF.
Remove the magazine from your Makarov, check the chamber to be sure it is unloaded. Point the gun in a safe direction with the safety off, and dry fire the gun but hold the trigger back, don't let it come forward. While holding the trigger back, with your off-hand push on the back of the hammer.
You will notice that you are able to push the hammer forward, into contact with the firing pin.
Now, release the trigger and allow it to come fully forward to rest. Again, push on the rear of the hammer.
You will now discover that you cannot move the hammer forward into contact with the firing pin.
The Makarov has a built in safety that allows the hammer to strike the firing pin only when the trigger is pulled completely to the rear. I'm comfortable with that level of safety, so I carry mine with the manual safety off. Of course, I make sure the firing pin channel is clean - if the pin is stuck forward, none of the safeties are adequate!