The guns come from the factory with the screw head flush with the frame. IF all the way in, or backed out was the right way to do it, I think the factory would do that.
Making a modification to the screw, or even adjusting it to a different position MAY result in something better suited to your desires, but is can also result in changing the reliability of the firearm, and not always for the better.
I was trained by the US Army Ordnance Center & School (1975) on the S&W revolver, and know the correct way to take them apart and put them back together.
A lot can be done to S&W revolvers to make them "feel better" in your opinion. As long as it is your gun, your opinion is the one that matters. If its not your gun, other people's opinions count more.
I don't touch the strain screw. generally speaking, unless I get a used gun with the screw all the way in, or standing proud, in which case, I turn it flush and see if the gun runs properly. If not, it gets repaired.