I've fired a friend's BFR .45-70 on several occasions. It's a REALLY BIG revolver! Very heavy (of course, it has to be, given what it's shooting!), very accurate and surprisingly controllable with standard-pressure loads (e.g. Remington 405gr. SP). On the other hand, with Garrett Hammerheads in the cylinder, it's the Beast From Hell to control! I also don't think it would long survive a diet of such powerful ammunition.
I guess it depends what you want it for. To have the "biggest and baddest" revolver on the block ("Don't tell me about your .475 Linebaugh - THIS is a REAL MAN'S revolver!"), it's great. For practical field use (e.g. hunting or silhouette shooting), I think it's just too big and heavy for comfort. I'd rather go with a Ruger Blackhawk or Redhawk in one or other version.