Alliant Bullseye and Unique have been the "standard" powders for the .45 ACP for nearly a century.
There are many satisfactory powders available today, but the aforementioned perform as well as they ever did.
230 grain plated bullets from Berry, Rainier or others, loaded to 800-825 FPS make excellent, easily controllable practice loads.
For ammunition to be used for serious social shooting, factory offerings loaded with state of the art bullets are quite difficult to duplicate by handloading.
I've recently done considerable research on .45 ACP defensive ammunition, and the consensus of most of those doing the testing is that the 230 Grain Winchester Ranger "T" series and the 230 grain +P Federal HST series are truly superb offerings, that meet IWBA criteria for expansion and penetration.