Not specific to the Pro-carry, but a couple of members of my IPSC club shoot Bull M5s ( makers of the Kimber frame), one in 45 the other in 40. the 40 is around the 3000 round mark, the 45 approaching 15000, all full power handloads. No problems at all when I've been around to watch. The frames have stood up well, with no noticable defects.
Radagast