There are many synthetics and many synthetic labs, and there is at least one man who makes a living just formulating new drugs and selling the 'patents'.
This stuff is not only far more dangerous, since it is manufactured by barrel lots of chemicals, not grown in the fields, there is no limit to production. It's harder to interdict something that can be sourced literally anywhere, takes up the space of a bathroom to produce.
Messing with dopamine levels is a recipe for disaster. Many psychotropic drugs are dopamine modifiers and psychotropics are prone to cause permanent damage, serious, unending, permanent damage to brain and nerve tissues. When you screw up on prescription psychotropics it is generally something minor, like a permanent tremor or say, maybe insanity, but these things add horrible complications. all you have to see to prove that is just look at some of the people around you who have had long term drug or alcohol problems, everyone of you knows somebody, someone who has spent twenty or thirty years drinking since you knew him in high school.
These people, these animals who are putting this stuff out for people to consume are just beyond tolerance. Ever since the first hippie smoked the first joint in some smelly flat in san francisco we have been fighting drugs, but it's just gotten exponentially worse because there are people who will spend the money and there are people who will take it.
BTW, the dissolution of muscle fibers is also caused by a genetic defect, it's really nasty. The muscles break down after being overused and you have billions of cells spilled into the blood stream. That isn't good.
If there is anything, really, anything at all that an individual can do to hamper the drug trade, it's a step. Don't let that stuff go on in your life or neighborhood.