I have no suppressors. My interest is supersonic. My bullet choices are approx 125 gr .Maybe Ballistic tips.
I don't look at ballistic numbers the same way I used to. If I'm going to use an AR with a 16 in plus bbl.the 5.56 has a lot going for it.
But,IMO,when bbl length gets down to 10 in pistol length, the 300 blk might be a more effective 100 yd cartridge,IMO.
It splits the difference between a 30 M-1 Carbine and 7.62x 39,even with a 10 in bbl it gets 2000 fps with a 125 gr 30 cal bullet.
Its at least as "adequate" as a 125 gr 357 magnum handgun load.
With the little Harbor Freight 2 in chop saw and the cartridge case fixture,converting 5.56 brass is easy. Same bolt,same magazine.I stock H-110 and small rifle primers.And 5.56 brass. Logistics are simple.
I'm not thinking of it as a big game round. Its not my choice for 250 yd prairie dogs.
My application is pretty much the same as a 30 M-1 carbine. A 10 inch AR pistol in 300 blk fills pretty much the same niche. Thats all I ask it to do.