havent got to use them yet, have a pound of 4451 and a pound of 7977. If you look on the Hodgdon reloading data online (Take Aim at Rifle Reloading), the 7977 looks to be a real winner in moderately overbore cartridges (in their advertising they say "the 7mm rem mag never had it so good!"). It shows top velocities for the 270 win with 150 and 140 grain bullets, it shows top velocities in .243 with 100-105 grain bullets, it shows very good velocities in the .300 win mag with all heavier bullets. I don't know about the other cartridges because those are the 3 I plan to use this powder in potentially. The 4451 is interesting too, but for now I'm more excited about 7977.