I have taken 2 deer with 357, one with a win 94 at about 60 yards, broadside shot, deer ran about 40 yards or so and tipped. 2 nd was with a smith 686 with 2x scope, was about 20 yards, sat right on the trail they were using, they came right down the trail, didnt see me, I couldnt belive how close they got before they saw me, they just stopped and looked at me funny, Shot was striaght on the the neck about 4-5 inches below the chin, dropped it right on the spot. Both does, and bullets were hand loaded 158 gr gold dots.