You should be able to load two at a time in a J or K frame. I am not sure if they are as compatible with the L frame, or GP100 size cyliner. I place the index finger along the back of the strip while bracing the cartridges between my my thumb and middle finger. I insert the first two and peel up and away, with the tip of my index finger as the pivot point. Repeat for the next two. I insert the last pair and grab the empty end of the strip to peel it away from the gun and drop it.
To do a 'tactical' reload, you open the cylinder, lightly push up on the ejector rod to raise the cartridges, then release it. With clean, dry chambers, the case expansion from the fired rounds should cause them to remain sticking out when gravity has dropped the others. Remove them, then re-charge with your Strip.