A family member has an American Derringer in .357 Magnum. Being a pipe fitter and owning a plumbing business on the side, he found himself sometimes going into bad areas at night to fix a cranky toilet. This guy is not a small man by any means and can handle just about anything in terms of recoil. I shot this derringer and found it misserable. The recoil is stout for a heavy gun. I am a fair shot but had a hard time putting two hits on an FBI "Q" target. And one hit on the paper didn't count!
Well, this relative didn't want to hear anything, thought his purchase was the absolute best thing, etc., etc. I took out my S&W J frame .357 Magnum, loaded it with the same cartridges being used in the derringer and we both did a presentation drill and fired two rounds on a target at 10' distance. My J frame came out from it's IWB holster and bang, bang, done. This was in a leisurely 2-3 seconds. I took a step back and looked over into the next lane and saw that he just got the derringer's hammer cocked. It took him about 10 seconds to put two rounds down range. And one of his missed as well.
Anyway, I agree that if you want one and your reson is to collect one as a novelty, then by all means do so. If you are looking at one as a serious defensive sidearm, look elsewhere. There are so many better defensive weapon platforms out there that offer more.