Every handgun is a set of compromises and you can only shoot one at a time. If you're going to have several, you don't need a bunch of general purpose handguns; each one should ideally suited to one purpose. Which one you need next depends and what you already have, as well as what possible uses you have. What area would you like to focus on next? Here are a few:
Home defense
Practicing quick draw/gun twirling
Pretty gun to fondle/collect
Historical gun to fondle/collect
Gimmick gun/novelty/conversation piece
Trail gun
Tin can plinker
Snake gun
Small game hunting, close range
Small game hunting, medium range
Concealed carry, pocket
Concealed carry, holster
Large game hunting, close range
Large game hunting, medium range
Large game hunting, long range
Target practice, small bore
Target practice, large bore
Target practice, indoor (air gun)
Target practice, competition (action games, SASS, etc...)