Because lead is slicker than copper, you can drive a heavier bullet faster than you can a JHP. In handguns. In modern infantry rifles of any caliber used since WW1, forget it.
Either gas-checking, hard-casting or both WILL solve leading problems. A gas check is a copper base-plate over the back end of the bullet, to act as a "heat shield" preventing the bullet's butt from burning off and plating the barrel during ignition. It's expensive by cast bullet standards, but usually the projectile is still cheaper than FMJs or JHPs.
You can get very expensive hardcast loads from Garrett, Buffalo Bore and the like, but you're not really paying for the bullets, you're paying for the R&D and expensive pressure-test gear needed to do very edgy loads safely.
The only other question is, can you get a "sharp cornered" flat nose ("meplat") to feed OK in a semi-auto? Depends entirely on the gun.
If I was kitting out US soldiers, I'd give them a backup snubbie wheelgun in 9mm with moon clips, with the rounds for same set up as nasty full wadcutters as a last-ditch "plan C" hideout gun. I'd make it 9mm so it can eat the same ammo as the full-size Beretta 9mm in a pinch. The Ruger LCR 357 set up as a 9mm would be a good platform for this critter that wouldn't break the bank bought in quantity.