Hello Willie
Frankly, handgun trajectories at general handgun ranges are pretty flat.
Yes, they do curve in a path called a parabola, but only over distance. Consider: According to the table at
http://www.chuckhawks.com/handgun_trajectory_table.htm a .45 ACP 230 grain hardball round - not famous for being a long range cartridge - when sighted in to strike 2.6 inches high at 25 yards, drops a monstrous 6.9 inches below the point of aim at 100 yards. So that's a nine and one half inch difference between 25 and 100 yards.
Most shooters can't shoot a ten inch group with a pistol at 100 yards, so there's no way to tell if the miss was because the sights aren't right or one just missed.
Bullet impact rises from the muzzle, because a pistol - or rifle - is actually pointed 'up' a bit. The muzzle is inclined so the bullet's path rises above the line of sight and then begins falling back and hopefully gets back to the line of sight exactly at the place one wants the bullet to strike. 25 or 50 yards for bullseye shooters, for instance.
The useful range of any round depends on the target. For paper or metal targets, getting bullet (point of impact) and target (point of aim) aligned is a mathematical problem; and starting points can be assumed or guessed in many cases. Then shooting is done to perfect the sight settings. For hunting game, one learns the outer limits of accuracy and sufficient power and then learns to estimate range and hold-over or under.
However, for self defense, a Government Model 45 ACP will generally hit a silhouette target out to 100 yards if the shooter can hold accurately. For deer hunting with a handgun at ranges out to 50 yards, the trajectory is essentially line of sight.
There are books on trajectory. I must confess I cannot recall any of them right now - except "The Bullet's Flight" by Mann. It's pretty technical, but covers the subject well. Amazon has one, a collector's item, for $200 or so.
You will learn more by simply learning to shoot well and keep notes of your targets, sight settings and experiences. Keep track of weather and lighting conditions, too. Bright light changes the way one's eyes see the sights. That in turn makes it seem the gun and ammo is shooting higher or lower. Or even off to the side if the light is low and angling from the side.