The Magtech 454 Casull ammo, like the majority of factory 454 ammo is very stout and well above what is needed for deer. If you are able to shoot those loads well, you can certainly use them successfully on deer. But many, or perhaps even most, people don't shoot 240 gr bullets at 1800 fps all that well. More power to those who do. Personally, I would look for something along the lines of 240 to 260 gr at 1000 to 1200 fps. Such a load will bring home the meat and be considerably easier to shoot well.