There were 7 hand ejector frames total:
M - tiny aka smallest hand ejector, 7 shot 22 long only. For the Ladysmith which was discontinued in the 1920s.
I - small frame, 22lr 32 S&W long and 38 S&W. Precursor to J frame but cylinder was too short for 38 special. Hold 5 shots 38 cal and 6 shots of either 22 or 32.
J - small frame (upgraded I) similiar to I frame but was elongated to accept 38 special rounds. 22, 32, 38.
K - 38 aka medium frame. 32-20, 32 S&W long (scarce), 38 special, 357 magnum, 32 H&R magnum, 22lr, etc. S&Ws most common frame size.
L - medium frame (upgraded). Frame was strengthened in key areas for 357 magnums. Many have a full lug underneath the barrel and the forcing cone does not have the 6 o'clock thin spot that the K frame 357s do. Heavy for its size, it reduces recoil and is favorite of many.
N - large aka 44 frame. This frame was conceived to marry the 44 special to a hand ejector. Made in a variety of calibers, this frame had cals from 38 special to 44 magnum and much in between. This frame is big and heavy, but not very heavy compared to other 44 frame offerings such as Ruger or Colt. 6 round capacity
X - extra large - 460 S&W mag or 500 S&W mag. This is a 5 shot frame, and is enormous. Commonly found with a muzzle brake, most (if not all) are tapped for a scope, and many are used for handgun hunting or long range handgun shooting. The most powerful mass produced revolver in the world.
My collection has all of the frames. The Ladysmith was the toughest to get.