Say what?
Are we shooting at paper, squirrel, Deer or an Elephant? Is the weapon a .22lr, 30-30 win or .416 Rigby? At 50 ft or 500 yds?
If you shoot a squirrel with a .416 Rigby at six feet then the Flat/Round nose is kinda irrelevant.
A flat nose bullet will expand quicker. So if you shoot a 30-30 win at a 150lb whitetail deer , black bear or hog under 200 yds then this great. 500lb Grizzy or even bigger Elk 300 yds+ not so much, you need the penetration. (easy, I know placement and ability matters more).
If I hit a deer, hog or any other target with a 24 - 30 inch mass using a 150 gr, 180 gr or 220 gr bullet at 2000 fps to 3500 fps it is passing through that target with out hesitation. How much penetration are you looking for?
Some believe that the slower velocity transfers more energy to the target.
So my question is what are you trying to accomplish?