My favorite caliber is .280 Rem. Many years ago, I bought a new Rem. Model 725 in the then new .280 Rem., and loved it. Since then, I've killed elk down to ground squirrels with it, and never have been dissatisfied with it.
I liked the .280 Rem. enough to have Frank Pachmayr build me a from-the-ground-up Pachmayr Custom in .280 Rem., on a cherry 1909 DWM Argentine Mauser action, 22" Apex bbl., Canjar trigger, etc., in 1978. Mr. Pachmayr walked me through his wood warehouse and helped me pick out the piece of Circassian Walnut, for the stock.
It, and my old Rem. 725, will both shoot 3/4" groups, when I do my part.
FWIW. J.B.