I'm only asking because I'm looking for a simple way to explain it.
Not true, 5.56 uses thicker casing. A .223 barrel cannot fire a 5.56, but a 5.56 can fire a .223Not a good analogy. 223 is just another name for 5.56. They are one and the same. There is a huge difference between 357 and 38.
5.56 uses thicker casing.