Delayed Reply to 22-250 with 52 Sierras and H414
Ben.....obviously I don't check this site often, sorry.
I use the combo you mentioned in my 22-250. I use 38 gr of H414, the 52 Sierra HPBT, federal lg rifle match primers. Seated at 2.515 into Remington brass....separated into lots of 50 by weight. Redding competition dies, Krieger barrel, BDL action, Jewell trigger, Leupold scope.
Tried lots of combos, this works best. Prairie dogs hate it.