I have three different presses.....
The first one I bought is an upgraded Lee three hole press. I upgraded it to four holes but now I see that was not all that necessary. I use it for the calibers that I shoot moderately. Black powder cartridge for .45-70, .45 LC, .38 Special, .357, Smokeless Tokarev, and when I get started, Makarov.
I have a good single stage Lee for special stuff and for a backup to the Lee multistage press. I have already broke the Lee twice and so the single stage was purchased to keep me going while waiting for parts.
I bought the Dillon because it became clear that I would be shooting .45 ACP and 9 mm Luger a lot. So this ammunition will be made in bulk, just right for the Dillon. The next caliber I will load from the Dillon is .380.