That's a good question, and having recently purchased multiple CZ's myself, I've also considered the issue quite a bit. My first question is whether you have a "B" model, which includes a firing pin safety. My understanding is that the safety plunger in the slide is depressed and deactivated only when you pull the trigger. In this case, if you carry cocked-and-locked, and the hammer somehow slips, it shouldn't cause an AD. If you carry in double action mode, with the hammer resting on the firing pin and a round in the chamber, the firing pin block should prevent an AD even with a sharp blow to the hammer, dropping the CZ on it's muzzle, etc.
If you have an 85 Combat or 75 Champion, both of these follow the original CZ design without a firing pin safety. You would theoretically need to be more careful in how you carry these weapons. I would prefer Condition 1 to double action carry with the hammer on a loaded chamber. With this in mind, you can request that your holster maker include a body-side shield with boning that will help prevent the safety from being accidentally clicked off when you carry in Condition 1.
I asked Mike, the head gunsmith at CZ, about this issue. He stated that the 85 Combat kept the old configuration without the firing pin safety because it was easier to strip without tools under combat conditions. The Champion is of course a competition weapon. The Combat and Champion firing pins are retained by a stop plate, similar to the 1911 and Hi-Power. The firing pins in the "B" models are retained by a rollpin, which requires a 1/8" punch to remove. In sum, for obvious reasons, Mike said that the "B" models are safer.
Personally, I've decided to carry my 85 Combat primarily in Condition 1, in a thumbreak holster that puts leather in front of the firing pin, or in a holster that provides extra security for the thumb safety.
I'd like to know your conclusions, too.