I wear an XL,or preferably a 2XXL glove. Work history from skidding fenceposts out of the woods,7 years busting tires and 30 years machinist, I have fairly meaty hands.
I take a high grip on a handgun.
On guns like a short spur 1911,a BHP,a PPK, the hide of the web of my hand just WILL roll up over the spur. I've found no grip or technique to avoid it.
Looking at the web of my hand shows a series of scars,like rungs of a ladder.
I hate bleeding on guns. It makes them rust.
I do appreciate the problem you are solving is real.
Beavertails work,of course, but I built a 1911 I wanted to appear in military trim.
A purist would notice,but I used a military long spur grip safety,lightly dehorned,and a slightly bobbed and dehorned GI type hammer.Not much, It does not bite me,and,IMO,it "looks right"
It still will properly disengage the grip safety when one handed de-cocking
(Think a Cavalry Troop,reins in one hand,lowering hammer to half cock. No,I'm not advocating carrying with the hammer on half cock. Perhaps from a military requirement,JMB designed the gun so thumbing the hammer fully back,the hammer spur against the grip safety spur would permit trigger pull to lower the hammer.)