What I’ve found with both my NMA and ROA is that no matter what projectile I use the more accurate powder charge does not seem to. I created a few bullet designs with Accurate Molds, and will be again as I’ve decided to make a universal bullet for the two revolvers. I intend to fill the excess room with mead by stretching my 195 grn version to about 210-230 grns I’m guessing.
Shot cheaper RBs and figure out what your gun likes. And since you are wanting to hunt with a small powder charge (my NMA likes 30 grns, which weighs 33, of 3F Olde Eynsford) I implore you to use sporting grade powders. There are only a few I’m aware of. Olde E, Swiss, and Triple 7, though some people seem to report that Pyrodex is also pretty powerful (there’s many others that say it isn’t). The other powders produce dismal velocities whereas the few I mentioned will get you into the standard .45 ACP levels of performance.
I also put in my designs meant for hunting also a wide meplat. They make bigger than caliber holes even at low velocities.
Oh, it was found that you do not want to load a bullet flush with the cylinder face as gas cutting will destroy your bullet nose. Don’t recall how much room was found to be needed. Something like 1/16” or so.
It was also found that the bullet doesn’t really need to be any more than 0.001” over chamber diameter. No need to cut a big ring of lead.
Also, for hunting with you didn’t mention, but it seems most states don’t allow it used during the muzzleloader season as it doesn’t load from the muzzle.