Each hand is a bit different, and grips are also usage dependent (e.g. combat vs range). The only way to be sure is to try them out yourself. Personally, I like wood grips, but when I shoot mags out of a k-frame, I like rubber grips. My hands are on the small/average size, so I can use most any k-frame grip, while the full size (covering the backstrap) n-frame grips leave me without enough purchase on the trigger.
And to top it all off, I am attracted to exotic grips (just like I like purty guns, I like purty grips), which sometimes means I am using grips that aren't well suited to me, but sure are purty.
I don't think that helped much, but that is my story.