Can a S&W 625 handle the .45 Magnum?

Not advisable. The Smith .45 Colts have very thin chamber walls, especially at the cylinder stop notches.
I won't risk it in mine.
Denis
 
Can a S&W 625 handle the .45 Magnum?
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Probably not.

It may be able to handle the .460 Rowland though. The .460 Rowland is "juicer" than the .45 Win Mag.
From Hodgdon's website:

.45 Win Mag
230 GR. HDY FMJ FP
COL: 1.555"

H4227 25.0 1259 29,400 CUP
H110 28.0 1410 29,000 CUP
HS-6 17.0 1296 36,600 CUP
HP-38 10.8 1191 37,100 CUP


.460 Rowland
230 GR. HDY XTP(Maximum Loads)
DIA. .451
COL: 1.270"

LONGSHOT 12.0 1336 39,200 CUP

Clark - http://www.clarkcustomguns.com/revserv.htm#rowland
will convert a 625 to .460 Rowland for $99.00

You can call them @ 888 458 4126 if you're serious about wanting a more powerful round and don't mind all the extra cost/effort.
It is cheaper though than it would be to pick up a model 29 or 629 in .44 Rem Mag. - which the .460 Rowland pretty much equals.
 
I used to have a Hawes single action 45 Magnum. That was a monstrous revolver. Far larger and heavier than my Webley MKVI. I would not try 45 Magnum in a S&W 625 as it is a thinwalled cylinder. The 460 Rowland seems to be a way of shortening the lifespan of a 625. It is like juicing nitrous oxide in a Scion.
 
if you need a magnum buy a magnum. enjoy the 625 for what it is because it is a very fine shooting revolver
 
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