Is the difference in caliber between .38 special and .45 long colt (or 45 acp). I've heard many times about bad fame of .38 in round nose configuration as man stopper ("widow maker" and other) cause presumed tendency of overpenetrate without stopping power and opposed a .45 bullet in same lrn configuration that should be a good man stopper. When we have lrn or other not expansive bullet style (wc/swc, lfp, fmj) and we have also enough energy to pass trough a uman body (but not adequate speed for hydrodynamical shock like .357) i think only diameter of the bull (and then of the wound) is the difference, but can a 0.09 inches make a difference? or the problem is retention of energy determines by weight of a .45 250 grs instead .38 158 when the bullet must pass through a bone? (.38 has not enough energy to do this?)