As mentioned previously, SC has no specific caliber restrictions for concealed carry. Obviously it must be legal to possess. The only restriction is on the size of the firearm as noted in the following cite:
"Concealable weapon" means a firearm having a length of less than twelve inches measured along its greatest dimension that must be carried in a manner that is hidden from public view in normal wear of clothing except when needed for self-defense, defense of others, and the protection of real or personal property. S.C. Code § 23-31-210(5) (2007).
Even in States with reciprocity, it may be useful to know if the State you are visiting has particular restrictions different than your State of residence. However, unless you are carrying something that is not really practical for concealed carry, I doubt you'll have any problems.