Not that I hunt much lately, but when I do, my muzzleloader is a reproduction of a .58 Enfield musketoon. I think the originals weren't rifled, but this one is. It's a short version of the Civil War era Enfield rifled musket, originally designed for cavalry use. It didn't work very well, so they never made many of them. However, for hunting, it makes a nice short handy package.
Anywho, the thing was designed for Minie bullets. I got a mold and cast .58 caliber, 610 grain flat nose Minies for it. Now, granted that rifled muskets have thin-walled barrels and can't handle overly powerful charges, but.. I gotta think that one of those Minies would anchor a whitetail pretty well.
The thing shot right to point of aim at 100 yards, at which range it was about six inch accurate. That's the best i could do with it anyway. It's good the sights were right on from the factory, because they were period military sights and weren't adjustable. Except that the rear is a ladder sight you can theoretically flip up for ranges out to 1000 yards or so. You try it first, I want to see how it's done before I try. With my eyes, I don't think I could see a man in a 19th century military uniform at that range, let alone a well-camouflaged whitetail buck! In fact, I doubt I ever could have.