My theory is that if one moves up from a standard cartridge to a magnum cartridge, he should take a heavier bullet over higher velocity. Heavier bullets when compared to lighter counterparts in the same caliber tend to have better sectional densities, better ballistic coefficients, hold their place in the wind better, and penetrate better. The lighter bullets would offer higher velocity, which in turn would give you a flatter trajectory, but it is far easier to estimate range than wind.
Bloodshot meat should not be a problem if you shoot behind the shoulder or for the neck, and recoil difference for any .270 caliber is negligible, regardless of bullet weight.
Bottom line is pick whichever takes your fancy, you don't have a bad choice out there.