I know from experience that our vests (Point Blank IIIA) will stop the following:
5 - 5.56x45mm
1- 12ga slug
2- 12ga 00Buck
10- .40S&W 180gr
We had a vest that was past its expiration date, so we took it to the range for a bit of "testing". Vest was hung on a rail at the end of the range, not placed over a semi-solid object. All shots were fired at a distance of 5 feet. Shots were fired, in that order, into a single vest, no trauma plates.
Now, all that being said, that's a heckuva lot of kinetic energy. Your insides would likely be turned to jelly. Regardless, I would not want to be shot with anything, vest or not.