Articulation is the key. Can you explain why you thought your life and others' were in danger? I'd say yes in this case.
Other things to think about in this situation. The car is being chased by officers. You opening fire may not be taken properly by the officers in pursuit. Also, one lesson learned at the academy. a 2oz bullet travelling at 900fps does not equal 3000lbs at 45mph.
On a crowded street with no cops in pursuit? Ok,but then, as others have stated, how can you determine that this person is committing a crime and not injured/unconscious/etc?
Which further begs the question, if someone is endangering your life in this way, can you still shoot them even if they are not malicious? What I'm saying is, allow that the driver is incapacitated and the car is careening down the sidewalk at a high rate of speed. This is obviously a danger to your life and the lives of others. However, the person has had a seizure and passed out. It is just dumb luck that the car has not stopped yet, but the foot is on the gas. Can you still justify shooting the person? Life and limb are threatened....