You may also wish to visit the thread about the Kimber ProCarry, and see my comments there.
I bought a 4506 as my first center-fire semi-auto. I (thought I) wanted a da/sa pistol. I made, for me, what turned out to be a poor choice. I never managed to get the hang of the trigger. The first shot went OK, but the pull on succeeding shots threw me off.
Accuracy was acceptable, but only that. It had the adjustable rear sight, and it liked to move around when bumped. I'd have to remember to push it to the left, against the screw, before stepping up to the line at league shoots.
Reliability was awesome! The example I had would feed, shoot, and extract anything I could find. Even when the pistol was disgustingly filthy, it ran fine.
The 4506 is a heavy brute! And, unless you're used to a Glock, it's fat. You can't compare it to a 1911, with regard to size and weight. My Kimber outshines it in ergonomics, size, weight, comfort, accuracy, and looks. The 4506 had a trigger best described as this: It's hard, it's long, and it's hard for a long time. I forget where I heard that , but it fits the 4506, whether DA or SA.
Others here have spoken in the past (unfavorably) about the slide-mounted safety. I poo-poo'ed their opinions. Until I used it, that is. I *really* like the 1911 safety. Generally, I carried it in condition 2 - chambered; hammer down. No need for a safety, except to de-cock, then back to "Fire" position. I think the magazine disconnect feature went away on mine, too. Who wants a pistol that can't be fired just because the mag is out?
Field stripping is simple - no tools needed. Watch that recoil spring, though. I had to repair the sheetrock once when it got away from me, launching the guide rod into the wall. Wear safety glasses when disassembling! Really.
I still, sometimes, lust after a 3913 for a small carry gun. Maybe Mrs. B. would like one...
JB