So many choices,,,
Ruger Mk II or Mark III - Great shooting guns at a good value price
Beretta NEOS - Same as above (4" has better balance than the 6".
Browning Buckmark - Great guns but a bit more pricey.
S&W 22A - nice handgun but mine was ammo picky so I sold it.
Walther p22 - Sold mine quick, it was a Jam-O-Matic.
There are many others but all told the Ruger and the Beretta are the ones I have been most happy with,,,
The Rugers are somewhat traditional in style,,,
The Beretta is very Buck Rogers (Han Solo for the younger crowd).
Hope this helps,,,