Generally, it's a waste of a slug as you are not utilizing the Brenneke's maximum performance in a smoothbore. ....
Absolutely, on a Rem.-1100, 870 and 1300. Very effective. I one took a 40-yd. running shot at a whitetail. Did not hit my spot but got into the vitals. Have taken closer shots as well. .....
Practice and;
Be Safe !!!