experience no. but i feel like it's too fast burning for the 308. especially from a non-autoloader.
while hodgdon does specify that if you use "light match bullets" it will work in the 308, the 150gr speer hot core doesn't exactly qualify.
feel free to try it, but i think you would like a slower burning powder better, and probably get better performance also.
see a "propellant burn rate chart" for more info.
something closer to the 4350's would work better.