Take YOUR rifle, the ammo you plan to hunt with, and set up targets at the longest range you consider an ethical shot.
Shoot at that distance and from field positions, so you see what your real world results are. You may find something a bit different from what books and the internet tell you. You may not. But you won't know, until you test it, yourself, with your gun.
There are two things that limit the useful range of EVERY cartridge. First, is how far you can see, and second is the shooter.
What limits useful range most is shooter ability.
Drop is a constant, on Earth. It is acceleration due to gravity. And while bullet drop, referenced to point of aim is different for every bullet and speed, it is constant for each bullet and speed. Meaning, it does not change.
Looking in the book, it says the standard Hornady .30 cal 150gr RN, at 2400fps, sighted for 100yds drops 7.9" at 200 and 30.0" at 300yds.
Change the bullet, the drop numbers change. Change the speed, the drop numbers change. What ever the drop is, it can be learned, if the shooter has the desire to. But there is a bit more to it, than that. The other part of the needed skill is being able to accurately know how far away your target is, and be able to compensate for the amount of drop that matches the distance.
Can you, personally see 8 inches at 200 yards. in order to shift your point of aim, enough, but not too much?? 30 inchs at 300??
Not a lot of people can. And almost no one who does not practice, can.
Knowing what your round does at every distance is the half the key, and being able to correctly compensate for the drop is the other half.
And, before that "key" can fit the "lock" you have to have the distance correct, or your results will be off. How much that matters depends on what you are shooting and how far off your distance estimate is.
This is the advantage to high velocity rounds, a bit of mis-estimation of the range doesn't change the drop as much as it can with slower rounds. That same 150gr RN at 2400 drops 2.5" by the time it gets to 150yds, but its 8" low at 200. And almost 17" low at 250yds.
The longer the range the more critical correct range estimation is, and more so with lower speed rounds than high speed ones.
IF you learn what your drop is shooting LeveRevolution ammo, then you learn what it is, from your gun. And you learn, what you can, and can't do in your hands. If it makes a difference in your hands, then its worth using. If not, why bother??