I have a Ruger 22/45, Ruger Mark II,and a Browning Buckmark. All are equally reliable with the Buckmark being the most accurate, and the 22/45 being the most indestructable. Like others have mentioned, the Smith and Wesson 22a/22s are not the same quality (actually nowhere near the same) although priced in the same range. My 22s is quite accurate though. More accurate than the other 3. Even at that, I would not recommend it unless you plan on shooting very, very very few rounds. Can't comment on the Smith 41, but what Cat says comes the closest to a critisism I have ever heard.
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