The only bad thing about APP is the price. I go through about 15 pounds a year in rifle & revolver shooting Frontier Cartridge class in CAS, but use KiK black powder in shotgun. I can get KiK delivered to my door for nearly half what I pay for APP. My last order of APP (20 pounds) was $19.69 per pound delivered, and my last order of Kik just a month ago (25 pounds) was $10.30 per pound, up from $9.80 or so just a couple months ago. Prices on both include shipping & hazmat.
The best deal going on APP (which I found after my last order) is from "coinguy" on gunbroker.com. A twelve pound case for $193.90, delivered, which comes out to about $16.16 per pound. Go to gunbroker and keyword "American Pioneer Powder" or do a search on coinguy.
I've tried APP both with and without lube, and no lube at all works better. In my side by side comparisons with gennywine black powder, APP also generates even more smoke than black, but not a lot of flames, so for night shoots, I go with black.
The longest I've ever gone without cleaning is a ten stage CAS match + some side matches over a three day period, so say maybe three hundred rounds through the rifle, and maybe a couple hundred through each revolver. No problem with fouling, and super easy cleanup, just hot water and a little Dawn detergent, a toothbrush here and there for the tight spots, a couple patches through the bore & chambers, a thorough blow down with compressed air, and an oiled patch through the bores & chambers again.