As far as increasing accuracy, I have not had much luck with trying to run bullets out that far. Amax or Sierra, in my 700. R 700's are famous for long throats.
Mine shoots PDG just the way it is, but you could have the barrel set back and chambered with a shorter throat. If I was going to do all that, I would just go for a custom bbl. chambered just the way I want.
I can hold 1/2 moa 5 shot groups pretty consistently, up to 250 yds, that is all the range I have around here without driving for hours.
Loading that long gives you very little bullet in the case and lowers pressure from a given powder charge, meaning you need a chronograph to make sure you are getting enough velocity to carry it on out there.
It is also very easy to knock the bullet out of true when your OAL is that long.