Also depends a lot on the angle at which you can shoot. Going through the ribs at 90 degrees is obviously different than shooting a hog looking straight at you.
Having been charged, I'd also say it depends on where you are standing at the time. I had one come from about 150 yds and nearly reach me, despite two good chest hits (and two marginal hits) with a 338.
Garrett, Buffalo Bore, and Cor Bon all make some real sledgehammer 44 loads. I've used the 320 gr. hardcast Cor Bons in a revolver with good results, but don't know whether the bullet length and shape would permit them to cycle well in a lever action rifle.
If you haven't bought already, consider the Marlin levergun in 45-70.