You can get small safe for your home. Many have a quick unlock feature and are designed to be bolted to a dresser or other large piece of furniture, to make theft harder, but still be close and easy to get to for bump in the night situations.
A true pelican case is very good for travel. They are tough and lock tight, and they are airline approved. In addition most have foam inside that is perforated in small squares to customize the fit by pulling out the shape you want. They come in many sizes... Keep a reusable desiccant pack inside it for gun storage.
Soft cases are for general protection from bumps... They will not prevent someone from getting to the gun very well.
It may be a little off the topic, but since this hasn't been brought up yet...
I suggest getting a small flashlight in the 100-150 lumen range. You need a light to identify an intruder before you fire in a home defense situation. You don't want to go brighter, as the light reflecting off of the walls will blind yourself... after spending a few hours sleeping in the dark that reflected light will hurt. So resist the urge to get the 1000 lumen wonder light some salesman may offer.
I recommend something around 6 inches long, light weight and has a tail cap switch. Also you want it to be a simple on/off affair, or if it does have multiple modes, that it does not cycle through them every time you click the switch. Needing a procedure like pressing and holding the switch to dim is fine, it can make the light useful for other things besides defense use. More than that is not needed, as the real world usefulness of things like strobe, are limited.
There are some simple techniques you can learn to use a handheld light and pistol at the same time.
Some may recommend a weapon mounted light, but I am not a fan of them. They may be a little easier and convenient, but the main focus of the light is were the pistol is pointing, and I find the idea of needing to point the pistol at what I want to see well, not a good idea.
One of my favorite brands is streamlight, but surefire and others will work well too.