About 10 years ago I hit a 300+ pounder (looked like a black volkswagon motoring through the woods) just behind the shoulder at about 80 yards using a 7mm mag and 160 Sierra Game Kings. The bullet traversed the torso and cracked 4 ribs on the off side, but did not exit. The hog still managed to go about 200 yards, before falling over. I still remember being dumbfounded that the pig was not rolled when he was hit. I watched the pig rock up from the impact and one of the tushes glint as it cought the sunlight coming through the trees; but it immediately spun around and high-tailed it the other direction, irrespective of the fact I had just shredded his lungs.
Earlier this year my son and I went pig hunting, using 7mm Mags and we both killed pigs. His not quite 250# (at 400 yards) and mine not quite 300# (at 70 yards). Both he and I shot our pigs just behind and little lower than the ear. Both pigs dropped like they were struck by the hammer of Thor.
I recommend head shots - find the ear, aim a little behind and low, exhale, pull the trigger; go collect the bacon.