Ok, Im guessing you are newer to reloading and I will try and break this down for you.
Not all cast bullets are the same, and this one is clearly not the same as the one in your lyman manual. Also not all guns are the same. What matters is that the round fits in your gun, think of the manual as a rough estimate. when you start loading a new bullet I generally load 2-3 dummy rounds with no crimp to make sure the seating depth works in my firearm using the plunk test method. Just keep adjusting them till they fit properly. there are also loaded cartridge gages, but if you just loading for one gun, your barrel is the best gage you will ever get.
With cast bullets in semiauto guns generally you should not have any of the lube groove showing. if it is showing it is not seated deep enough.
Lastly, work your load up from the starting load! DO NOT jump straight to a recommended load. most manuals have a start and a max, they are there for a reason. Load up 5-10 or so at start and shoot them, see how they behave. Progress from there.
Ok, I just pulled out my lyman 50th, and we have another issue, you appear to possibly be over max.
Lyman 50th, 45 auto, 225g cast bullet (mold#452374) shows a recommended starting load of 4.5g of titegroup, and a MAX of 5.1g of titegroup. Im hoping you mis-typed.
What I would recommend is loading to the length that will fit in your gun, load 5-10 with the STARTING load from the manual, and shoot them and see how they shoot in your gun.
The listed starting loads in my Lyman 50th for 225g cast lead are as follows, and this is where I would start. If your concerned with the bullets being seated deeper and the reduced case capacity you could reduce these by 0.5g and start there.
Listed starting charged
Titegroup 4.5g
Unique 5.5g