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There are three things that should prevent you from firing a .45 super in your High Point. 1. Recoil force. 2. Slide velocity. 3. Case head support. The recoil spring in your HP is regulated for .45 acp recoil energy. The weight of the slide and the resistance of the recoil spring work together to ensure that the slide does not begin to move backward thus unlocking the barrel from battery, before the peak pressures have subsided in the chamber. When you dramatically increase the recoil force and/or the slide speed, you push the dynamics of reliable operation way out of balance. At the very least, the slide will brutally slam back against the slide stop with enough force to possibly damage your gun. Also, if the barrel does not have VERY GOOD case head support, you run the risk of a ruptured case. At .45 super pressures, this is something you want to avoid at all costs. You might get away with it a time or two, but the consequences of having a "bad gun" day would be very unpleasant. I shoot a Springfield V16 Longslide in .45 super, so I am fully aware of the power in this little beast. The recoil is on par with a .44 magnum, only worse, as this gripframe was not designed with this kind of recoil in mind. But the muzzle blast is worse than a .44 mag. The v16 has two long rows of vent holes near the muzzle that help keep the muzzle down somewhat, but the blast from these vents is quite severe. Anyway the .45 super should only be fired in semi-autos that have been designed, or modified to do so. There are a few revolvers that can shoot the super round. Dan Wesson made a large frame DA a while back that would shoot .45 acp, .45 super, .460 Rowland, and .45 Winchester mag. Ruger makes a .45 Blackhawk/Vaquero convertable (old models only) that can safely handle it. (though if you asked Ruger, they would insist that it is unsafe), Even though handloaders routinely shoot .45 colt reloads that go beyond 44 mag power in these "strong as h*ll guns. Basically...to make a short story long.....please don't try it in your HP....I know these guns are very inexpensive, and if you damaged it the financial loss wouldn't put you in the poor house, but you could really get hurt bad if the gun let go in your hand....