In the general handgun section weshoot2 mentioned a major 45 colt load I think. I would like to see what the hottest 44 mag loads compare to it for reference I guess.
And on sixgunner they had a 12+ page argument over the 45 colt and the 44 magnum and power held within each one. Excellant site, I actually slowly read every post in their history and learned a lot.
For new brass and new rugers, 45 colt wins handloading. But some old 45 colt brass and most if not all 45 colt old firearms should be carefully checked. It was also interesting that some who bought 45 colt chambered rugers would find either the cylinder or bore of the barrel a bit small, and this caused lots of leading when shooting lead rounds. They actually have kits for taking care of this if you do some research. Some did not need to open things up, but many did. The 44 mag did not seem to have this problem, I have not taken the time to check mine out.
I got a couple 44 mag rugers earlier this year, redhawk and super blackhawk. I already had a lever action in 44 mag and figured I would be plenty happy with hot 44 mag loads for the time being.
Of course those durn birds head ruger single actions don't come in 44 magnum and I am too cheap to really want to swap grips around.
Check price of rounds if you will not be reloading much or at all for a while. Some say it is so much easier to find 44 mag, but I think 45 colt should become more available soon.